09/11/25 Health Advisory: 2025–2026 respiratory-illness season vaccine recommendations

Gloved hand squeeze bicep while giving a shot.

Summary

  • Everyone 6 months or older should get seasonal flu vaccine.
  • Everyone 6 months or older should get 2025–26 COVID-19 vaccine.
    • Moderna approved for 6 months and older.
    • Pfizer approved for 5 years and older.
    • Novavax approved for 12 years and older.
  • Stop giving last year’s (2024-2025) COVID-19 vaccine formulation.
  • Updated RSV (respiratory syncytial virus) recommendation for older adults:
    • Everyone 75 years and older should get RSV vaccine,
    • as should those 50–74 years old at increased risk of severe RSV.
  • Abrysvo vaccination for pregnant people 32-36 weeks gestation began Sept. 1.
  • RSV monoclonal antibody administration for babies and eligible toddlers begins Oct. 1.
  • Co-administration of COVID-19, flu, and RSV vaccines is safe.
  • Vaccination is one of the best ways to prevent severe disease and hospitalization.

COVID-19 vaccine recommendations

Washington State Department of Health (DOH) continues to recommend everyone 6 months and older, including pregnant people, stay up to date with the current COVID-19 vaccine to help protect against severe illness, hospitalization, and death. DOH supports evidence-based recommendations from trusted national medical associations including the American Academy of Pediatrics for those 6 months-18 years, the American College of Obstetrics and Gynecology for all pregnant people, and the American Academy of Family Physicians for adults 19 years and older. DOH provided a statewide standing order to assist providers.

For most people, the minimum interval between their last COVID-19 vaccine dose and their updated dose is 8 weeks. There are exceptions for people completing a multidose initial vaccination series, including:

  • Children 6 months–4 years old.
  • Anyone 6 months or older who is moderately or severely immunocompromised.
  • People 12 years or older who get Novavax.

For full schedule details, follow DOH’s COVID-19 Vaccine Schedule as recommendations vary based on age, comorbid conditions, and vaccination history. Learn more about Washington State’s COVID-19 vaccine recommendations:

Flu vaccine recommendations

  • CDC and DOH recommend everyone 6 months or older get updated 2025–26 flu vaccine to reduce the risk of flu and its potentially serious complications.
  • Some children 6 months–8 years old need 2 doses of flu vaccine, including those who:
    • Are getting flu vaccine for the first time.
    • Previously got only 1 dose of flu vaccine.
    • Have an unknown vaccination history.
  • People who are pregnant or might be pregnant during flu season should get flu vaccine.
  • Pregnant people and those with certain medical conditions or those who are immunocompromised should not get live, attenuated intranasal flu vaccine.
  • Adults 65 years or older are recommended to preferentially get high dose, recombinant, or adjuvanted flu vaccine.
  • It is ideal for most people to get flu vaccine in September or October. Continue to offer flu vaccine throughout the season, as long as flu viruses are circulating.
  • All flu vaccines are trivalent this year.
    • Egg-based vaccines:
      • A/Victoria/4897/2022 (H1N1)pdm09-like virus.
      • Updated A/Croatia/10136RV/2023 (H3N2)-like virus.
      • B/Austria/1359417/2021 (B/Victoria lineage)-like virus.
    • Cell- or recombinant-based vaccines:
      • A/Wisconsin/67/2022 (H1N1)pdm09-like virus.
      • Updated A/District of Columbia/27/2023 (H3N2)-like virus.
      • B/Austria/1359417/2021 (B/Victoria lineage)-like virus.

RSV prevention recommendations

To protect infants and young children

CDC recommends choosing 1 of these to protect infants and young children against severe RSV:

  • Abrysvo RSV vaccine during pregnancy.
  • RSV immunization for infants and some older babies.

Most infants will not need both.

Abrysvo maternal vaccination

  • Administer Sept. 1–Jan. 31.
  • 1 dose between 32–36 weeks gestation.
  • Abrysvo is the only FDA-approved RSV vaccine for pregnant people.

RSV monoclonal antibody

  • Administer Oct. 1–March 30.
    • For infants born during this time, monoclonal antibody should be administered within 1 week of birth, ideally at the hospital.
  • CDC and DOH recommend RSV monoclonal antibody for infants if:
    • The mother did not get RSV vaccine during pregnancy.
    • You don’t know the mother’s RSV vaccination status.
    • The infant was born within 14 days of maternal RSV vaccination.
  • Two products are available this season:
    • Clesrovimab (Enflonsia): 1 dose for infants less than 8 months of age regardless of weight entering their first RSV season. Not recommended for infants 8 months or older.
    • Nirsevimab (Beyfortus):
      • 1 dose for infants less than 8 months of age (50 mg for infants <5 kg and 100 mg for infants ≥5 kg) entering their first RSV season.
      • 200 mg dose administered as 2 IM injections (2 x 100 mg) for children up to 24 months of age, regardless of body weight, who remain vulnerable in their second RSV season. This includes children who:
        • Are American Indian or Alaska Native.
        • Have chronic lung disease of prematurity and require medical support during the 6 months before the start of their second RSV season.
        • Have severe immunocompromise.
        • Have severe cystic fibrosis.
  • Except in rare circumstances, infants younger than 8 months who are born 14 or more days after their mother got RSV vaccine don’t need RSV monoclonal antibody. Learn more about special situations and populations.

RSV recommendations for adults

  • 3 RSV vaccines are licensed for use in adults 50 years or older:
    • Arexvy by GSK.
    • mRESVIA by Moderna.
    • Abrysvo by Pfizer.
  • CDC recommends 1 single dose of RSV vaccine for:
    • Adults 75 years or older.
    • Adults 50–74 years old who are at increased risk of severe RSV disease because of things like:
      • Cardiovascular disease.
      • Lung disease.
      • End-stage renal disease or dependence on hemodialysis or other renal replacement therapy.
      • Diabetes mellitus with end-organ damage.
      • Severe obesity.
      • Liver disorders.
      • Neurologic or neuromuscular conditions.
      • Hematologic disorders.
      • Moderate or severe immune compromise.
      • Living in nursing homes or other long-term care facilities that assist with activities of daily living.

Other chronic medical conditions or risk factors that a healthcare provider determines might increase the risk of severe disease due to respiratory infection.

More resources:


Questions?

Contact Jefferson County Public Health at (360) 385-9400.